PLAVIX by Aventis and Bristol-Myers
A new study by the Mayo Clinic has found that adding the anti-clotting drug clopidogrel (Plavix) to a daily dose of aspirin — compared with aspirin alone — does not reduce the risk of heart attack or stroke for people at high risk of developing cardiovascular disease. In fact, if you don't have a history of cardiovascular disease, combining Plavix and aspirin may do more harm than good.
PLAVIX, also known as Clopidogrel, is an antiplatelet medication that was approved by the U.S. Food and Drug Administration in November of 1997 to reduce the risk of heart attack, stroke, or vascular death in patients with established peripheral arterial disease (PAD) or acute ST-segment elevation myocardial infraction (STEMI). Internationally, Plavix is sold as Iscover.
How Plavix Works
Plavix has been dubbed a “superaspirin” blood-thinner. Plavix helps keep platelets, particles in your blood, from sticking together and forming clots. This helps keep blood flowing and protects you from a future heart attack or stroke.
Clot formation is a natural defense mechanism of the body to protect you from excessive bleeding in the case of an injury. When you cut yourself, platelets stick together to form a clot. Clot formation can also be triggered by the rupture of plaque, which is a buildup of cholesterol and other materials in the walls of the arteries. When platelets clump together on or near the plaque, they can form a clot that may limit or completely stop the flow of blood to various parts of the body. If a clot forms in an artery leading to the heart, a heart attack can occur. If a clot forms in an artery leading to the brain, a stroke can occur.
Note - Do not change medications without first consulting your doctor.